リンパ関連の病理学において、科学の発展により、近い将来、大きな進歩が見られるであろうことは予想できますが、しかし、今のところ、効果的な治療法は見つかっていないのが現状です。そこで、現代医学の世界とは離れて、以下の現実にあった例を紹介しますが、これは世界的に非常に注目を集めた「出来事」でした。
2000年4月、当時のローマ教皇ヨハネパウロ２世の了解のもとに、バチカンは、リンパ浮腫の超自然的な治癒を行ったことで知られていたポーランド出身の修道女ベアタ・ソル・ファウスティーナを、聖人に列することを決めました。このファウスティーナという修道女は、生前、非常に敬虔な信仰心を持ち、時折、キリストと会話をしたことでも知らせていますが、「奇跡的な出来事」として知られているのは、その死後に起きました。アメリカ合衆国のモーリーン・ディガンという女性が、原発性のリンパ浮腫に侵されていましたが、この修道女の墓の前で祈ることによってそれが治癒した、というものでした。この奇跡的な治癒は、その後、バチカンにおいて、何年もの間あらゆる調査が行われ、また５人のそれぞれ独立した専門医によっても認められました。説明のできないこの治癒は、科学分野とカトリック・キリスト教世界において、まさに奇跡として語られています。
さらなる情報はこちら:
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ドキュメンタリー: モーリーン・ディガンのストーリー（英語）
ドキュメンタリー: 「オーシャン・オブ・マーシー（神の慈悲の海）」（英語）
新聞記事:
ワシントンポスト紙（英語）:
関連事項
リンパ浮腫の発症
および有病率に関する情報
Traducción / Translation
EXTENDED VERSION
Although science forecasts for the near future great breakthroughs toward resolving diseases of the lymphatic circulatory system, to this day no definitive treatment is known. Surprising is, therefore, the following facts that once drew worldwide attention.
On the 30th of April 2000, by the mediation of Pope John Paul II, the Vatican canonized Blessed Faustina, recognizing the intercession and supernatural cure of a person with Lymphedema. The case of the North American lady Maureen Digan, born with Primary lymphedema (Milroy Disease), was accepted after the recognition of 5 independent medical specialists, and several years of intense ecclesiastical research, as something inexplicable to science, and miraculous for the church.
There is no medical explanation for Maureen’s healing, lymphedema is a chronic disease due to a permanent blockage in the lymphatic system which prevents fluid from draining and causes a fluid buildup and complications due to the swelling. Even though the majority of Lymphedema can be controlled with compression treatment, there is still no cure and unfortunately, it does not respond to medication and does not go into remission.
Maureen Digan, who already had lost one leg to lymphedema due to the infections, recalled that when she was healed she felt an instant change in her leg. At Faustina’s tomb, she said that all of a sudden she could feel the leg changing, she stuffed her shoe with a napkin so it wouldn't fall off, however, she waited until she was back in her hotel room to check her leg. When she did, her swollen leg which was also due to be amputated shortly, was back to its original size, it looked normal and the swelling and pain were gone, her disease had disappeared completely. Her doctors couldn’t explain what happened.
The Vatican institutes stringent guidelines for what constitutes a miracle. A cure must be sudden, complete, lasting, and—most importantly—inexplicable by contemporary science. The Church privileges medical testimony, which scrutinizes the evidence submitted concerning facts and dates. Very few alleged miracles make it past the Consulta Medica, as the body is called. In miracle tribunals, a cure is assumed natural until proven otherwise, a position arrived at through a lengthy process of elimination, which is centered on a forensic, even skeptical, approach to the assertion, argument, and interpretation. When the tribunal thinks its work is complete, its members seal all documents in a ceremony and send them to Rome.
As to the ultimate cause of Maureen Digan's spontaneous regression of lymphedema, the judgment was unanimous: her cure was quick, complete, lasting, and inexplicable to science. Her case was well evidenced, well-proven, well documented, and well biopsied that she suffered an incurable disease.
Even when a supernatural phenomenon is determined by the Church to be the real thing, it can take years to authenticate. This particular event was accepted by the Sacred Congregation for the Cause of Saints in 1991 as the miracle needed for Faustina’s beatification, which took place on April 18, 1993. (Her canonization was on April 30, 2000).
References:
(Click on the texts to see videos and to read the articles)
On the 30th of April 2000, by the mediation of Pope John Paul II, the Vatican canonized Blessed Faustina, recognizing the intercession and supernatural cure of a person with Lymphedema. The case of the North American lady Maureen Digan, born with Primary lymphedema (Milroy Disease), was accepted after the recognition of 5 independent medical specialists, and several years of intense ecclesiastical research, as something inexplicable to science, and miraculous for the church.
There is no medical explanation for Maureen’s healing, lymphedema is a chronic disease due to a permanent blockage in the lymphatic system which prevents fluid from draining and causes a fluid buildup and complications due to the swelling. Even though the majority of Lymphedema can be controlled with compression treatment, there is still no cure and unfortunately, it does not respond to medication and does not go into remission.
Maureen Digan, who already had lost one leg to lymphedema due to the infections, recalled that when she was healed she felt an instant change in her leg. At Faustina’s tomb, she said that all of a sudden she could feel the leg changing, she stuffed her shoe with a napkin so it wouldn't fall off, however, she waited until she was back in her hotel room to check her leg. When she did, her swollen leg which was also due to be amputated shortly, was back to its original size, it looked normal and the swelling and pain were gone, her disease had disappeared completely. Her doctors couldn’t explain what happened.
The Vatican institutes stringent guidelines for what constitutes a miracle. A cure must be sudden, complete, lasting, and—most importantly—inexplicable by contemporary science. The Church privileges medical testimony, which scrutinizes the evidence submitted concerning facts and dates. Very few alleged miracles make it past the Consulta Medica, as the body is called. In miracle tribunals, a cure is assumed natural until proven otherwise, a position arrived at through a lengthy process of elimination, which is centered on a forensic, even skeptical, approach to the assertion, argument, and interpretation. When the tribunal thinks its work is complete, its members seal all documents in a ceremony and send them to Rome.
As to the ultimate cause of Maureen Digan's spontaneous regression of lymphedema, the judgment was unanimous: her cure was quick, complete, lasting, and inexplicable to science. Her case was well evidenced, well-proven, well documented, and well biopsied that she suffered an incurable disease.
Even when a supernatural phenomenon is determined by the Church to be the real thing, it can take years to authenticate. This particular event was accepted by the Sacred Congregation for the Cause of Saints in 1991 as the miracle needed for Faustina’s beatification, which took place on April 18, 1993. (Her canonization was on April 30, 2000).
References:
(Click on the texts to see videos and to read the articles)
- DOCUMENTARY: MAUREEN DIGAN TELLS HER STORY (In the following video we can see Maureen Digan telling her story and Doctor Kenneth Gershengorn speaking about the clinical case)
- FULL 1987 DOCUMENTARY FILM NARRATED BY OSCAR-WINNING ACTRESS HELEN HAYES - THE LIFE OF ST. FAUSTINA KOWALSKA
INFORMATION ON LYMPHEDEMA
(Click on the texts to read the research articles)
SCIENTIFIC SOCIETIES
PATHOPHYSIOLOGY
- lymphedema.
- Biology of Lymphedema
- Lymph vessels: the forgotten second circulation in health and disease
- Lymphatic Vessel Network Structure and Physiology
- Lymphatic System Flows
- Organ-specific lymphatic vasculature: From development to pathophysiology.
- The lymphatic vascular system: much more than just a sewer.
- The unresolved pathophysiology of lymphedema.
- Lymphedema: A Practical Approach and Clinical Update.
- Coagulation in Lymphatic System.
- Regulation of immune function by the lymphatic system in lymphedema.
- Oxidative stress in chronic lymphoedema.
- Regulatory T Cells Mediate Local Immunosuppression in Lymphedema.
- Hemostatic properties of the lymph: relationships with occlusion and thrombosis.
- Secondary lymphedema: Pathogenesis
- Gastrointestinal Lymphatics in Health and Disease
- Intestinal lymphangiectasia in adults
- Role of the lymphatic vasculature in cardiovascular medicine
- The lymphatic vasculature in disease
- Lymphoscintigraphic abnormalities in the contralateral lower limbs of patients with unilateral lymphedema.
- The Prevalence of Lower Limb and Genital Lymphedema after Prostate Cancer Treatment: A Systematic Review
- Peripheral Edema
CUTANEOUS COMPLICATIONS
- The lymphatic system and the skin. Classification, clinical aspects, and histology.
- Lymphedema and cutaneous diseases.
- Lymphedema and subclinical lymphostasis (microlymphedema) facilitate cutaneous infection, inflammatory dermatoses, and neoplasia: A locus minoris resistentiae.
- Serum Immune Proteins in Limb Lymphedema Reflecting Tissue Processes Caused by Lymph Stasis and Chronic Dermato-lymphangio-adenitis (Cellulitis).
INFECTIOUS COMPLICATIONS
- Lymphatic Flow: A Potential Target in Sepsis.
- Infectious complications of lymphedema.
- Acute inflammatory exacerbations in lymphoedema.
- Inflammatory Manifestations of lymphedema.
CELLULITIS / DERMATOLYMPHANGIOADENITIS
- Cellulitis.
- Clinical features, microbiological epidemiology, and recommendations for the management of cellulitis in extremity lymphedema.
- Challenges of cellulitis in a lymphedematous extremity.
- Diagnosis and management of cellulitis.
- Cellulitis risk factors for patients with primary or secondary lymphedema.
- Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg.
- Prevention of dermatolymphangioadenitis by combined physiotherapy.
- Erysipelas: a common potentially dangerous infection.
TUMOURS
- Malignant tumors as complications of lymphedema.
- Lymphedematous areas: Privileged sites for tumors, infections, and immune disorders.
- Lymphedema-related angiogenic tumors and other malignancies.
- Lymphedema: an immunologically vulnerable site for the development of neoplasms.
- Lymph stasis promotes tumor growth
- A retrospective analysis of Stewart-Treves syndrome in the context of chronic lymphedema.
- Stewart-Treves Syndrome
PAIN
- Congenital lymphedema complicated by pain and psychological distress: case report
- Lymphatic Pain in Breast Cancer Survivors
- Does Manual Lymphatic Drainage Have Any Effect on Pain Threshold and Tolerance of Different Body Parts?
- Lymphedema therapy reduces the volume of edema and pain in patients with breast cancer
- Quality of life in patients with primary and secondary lymphedema in the community
TREATMENT
- Treatment of limbs lymphedema.
- Nonoperative treatment of lymphedema.
- Lymphedema: From diagnosis to treatment.
- Lymphedema-clinical picture and therapy.
- Physiotherapeutic rehabilitation of lymphedema: state-of-the-art.
- Diagnosis and management of lymphatic vascular disease
- Effective treatment of lymphedema of the extremities.
- Lymphoscintigraphic aspects of the effects of manual lymphatic drainage.
- Intensive Treatment of Lower-Limb Lymphedema and Variations in Volume.
- Effectiveness and safety of Complete Decongestive Therapy of Phase I.
- Therapeutic Efficacy of Complex Decongestive Therapy in the Treatment of Elephantiasis of the Lower Extremities.
- Effects of Phase I complex decongestive physiotherapy on physical functions and depression levels in breast cancer-related lymph edema.
- Does lymphoedema bandaging reduce the risk of toe ulceration?
- Study of 700 referrals to a Lymphedema Program.
- Worldwide assessment of healthcare personnel dealing with lymphoedema.
- Földi M, Földi E. Földi’s textbook of lymphology for physicians and Lymphoedema therapists.
- Fluid Shifts Induced by Physical Therapy in Lower Limb Lymphedema Patients
- Visualization of Accessory Lymphatic Pathways, before and after Manual Drainage, in Secondary Upper Limb Lymphedema Using Indocyanine Green Lymphography
- The risk of genital edema after external pump compression for lower limb lymphedema.
- The management of genital lymphoedema
- The management of deep vein thrombosis in lymphoedema: a review.
- Lymphedema-associated comorbidities and treatment gap.
COMPRESSION GARMENTS
- A study of the advantages of elastic stockings for leg lymphedema.
- Indications for medical compression stockings in venous and lymphatic disorders: An evidence-based consensus statement.
- Medical compression stockings for chronic venous diseases and lymphedema: Scientific evidence and results of a patient survey on quality of care.
- Impact of Compression Therapy on Cellulitis (ICTOC) in adults with chronic edema: a randomized controlled trial protocol.
- Compression Therapy Is Cost-Saving in the Prevention of Lower Limb Recurrent Cellulitis in Patients with Chronic Edema.
- Occupational leg edema-use of compression stockings.
DISABILITY
- Disability and lymphedema.
- Lymphedema and employability.
- Worse and worse off: the impact of lymphedema on work and career after breast cancer
- Functioning in lymphedema from the patient's perspective using the International Classification of Functioning, Disability and Health (ICF).
- Unilateral upper extremity lymphedema deteriorates the postural stability in breast cancer survivors
- Postural Stability in Patients with Lower Limb Lymphedema
- Disability, psychological distress and quality of life in breast cancer survivors with arm lymphedema
DISFIGUREMENT
- Adjusting to disfigurement: processes involved in dealing with being visibly different
- Quality of Life in Cancer Patients with Disfigurement due to Cancer and its Treatments
- Quality-of-life and body image impairments in patients with lymphedema
- Association of lower extremity lymphedema with pelvic floor functions, sleep quality, kinesiophobia, body image in patients with gynecological cancers
QUALITY OF LIFE
- The impact of lower limb chronic oedema on patients' quality of life
- Quality of life in patients with primary and secondary lymphedema in the community
- Evaluating the effect of upper-body morbidity on quality of life following breast cancer treatment.
- Functionality and quality of life of patients with unilateral lymphedema of a lower limb: a cross-sectional study
- The effect of complete decongestive therapy on the quality of life of patients with peripheral lymphedema
PSYCHOSOCIAL IMPACT
- Psychosocial Impact of Lymphedema.
- Associations between chronic disease, age and physical and mental health status
- A network analysis of psychological flexibility, coping, and stigma in dermatology patients
- 'Abandoned by medicine'? A qualitative study of women's experiences with lymphoedema secondary to cancer, and the implications for care
- People are neglected, not diseases.
- Chronic edema/lymphoedema: under-recognized and under‐treated.
- Lymphatic Medicine: Paradoxically and unnecessarily ignored.
- Medical education: a deficiency or a disgrace.
PEDIATRIC LYMPHEDEMA
- NORD: Rare Disease Database - Lymphedema
- Medical management of lymphedema.
- Primary lymphedema in childhood.
- An approach to familiar lymphedema
- Pediatric Children Lymphedema
- Primary Lymphedema French National Diagnosis and Care Protocol (PNDS).
- Lymphatic filariasis: an infection of childhood.
- Lymphatic filariasis in children: clinical features, infection burdens and future prospects for elimination.
LYMPHATIC FILARIASIS / PODOCONIOSIS
- Podoconiosis: Clinical spectrum and microscopic presentations.
- Podoconiosis: A Possible Cause of Lymphedema in Micronesia.
- A cross-sectional study to evaluate depression and quality of life among patients with lymphoedema due to podoconiosis, lymphatic filariasis, and leprosy.
- The impact of acute adenolymphangitis in podoconiosis on caregivers.
- Neglected tropical diseases and disability-what is the link?
- Locomotor disability in bancroftian filarial lymphoedema patients.
- Neglected patients with a neglected disease?
- Neglected tropical diseases and mental health: a perspective on comorbidity.
- People are neglected, not diseases.
- Addressing Inequity: Neglected Tropical Diseases and Human Rights.
- Neglected Tropical Diseases, Conflict, and the Right To Health.
BLOOD VASCULAR SYSTEM
- Peripheral Edema
- Phlebolymphedema
- Understanding Chronic Venous Disease: A Critical Overview of Its Pathophysiology and Medical Management
- Role of the lymphatic vasculature in cardiovascular medicine
- Communication between lymphatic and venous systems
- Phlebopathies and occupation
- Phlebopathies and workers
- Evidence of health risks associated with prolonged standing at work and intervention effectiveness
- Leg edema formation and venous blood flow velocity during a simulated long-haul flight
Articles that may also interest you:
(Click on the texts)
WHAT IS THE BEST TREATMENT OPTION FOR PAEDIATRIC AND PRIMARY LYMPHOEDEMA?
WHAT ARE THE PRINCIPAL FUNCTIONS OF MANUAL LYMPHATIC DRAINAGE
WHAT ARE THE MAIN DIFFERENCES BETWEEN THE TWO PRINCIPAL LYMPHEDEMA TREATMENT PROTOCOLS
WHAT ARE THE STRATEGIES FOR THE IMPLEMENTATION OF LOW-COST TREATMENT OPTIONS FOR LYMPHEDEMA
WHY IS A BUTTERFLY THE SYMBOL OF LYMPHEDEMA?
WHAT DOES INTERMITTENT PNEUMATIC COMPRESSION PUMP THERAPY (IPC) DO, AND DOES NOT DO FOR LYMPHEDEMA?
